The Mark of the Beast-
"And he causeth all, both small and great, rich and poor, free and bond, to receive a mark in their right hand, or in their foreheads: and that no man might buy or sell, save he that had the mark, or the name of the beast, or the number of his name. Here is wisdom. Let him that hath understanding count the number of the beast: for it is the number of a man; and his number is Six hundred threescore and six" (Revelation 13:16-18).
We cannot interpret this number (666) literally; we have to have the wisdom of God - "Here is wisdom" (Revelation 13:18). (2 Thessalonians 2:3) speaks of "that man of sin." That word "man" in Greek is "anthropos," which can mean "mankind," a corporate body of men. It’s not talking about a particular individual.
"Anthropos" is the word used in (2 Timothy 3:17) "That the man of God may be perfect, thoroughly furnished unto all good works." "Man of God" is not referring to a man or one man, but rather to every man of God. Likewise, the number of the beast is not referring to one man; it’s every man under the devil’s influence and part of the beast’s system.
In the Scriptures, "six" is the number representing man, so 666 stands for man at his highest level apart from God. That 666 is marked on the right hands and the foreheads representing conformity to the image of the beast, thinking Satan’s thoughts and with the hands doing his evil works.
Hands are symbolic of strength. The Bible tells us we’re to love God with all of our heart, all of our soul, all of our strength, and all of our mind (Luke 10: 27). The strength of my hands should be used to glorify God, but those marked by the beast will use the strength of their hands to do evil works.
This describes the beastly system’s infiltration into mankind. Men are being marked by the beast without even realizing it because they’re expecting one individual antichrist and a literal tattoo while spiritually they are already marked by the world.