22.When had the Christians in Philippi assisted Paul with material support?

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When he left Macedonia and travelled south to preach the Gospel in Corinth.

Paul had preached in Philippi (Acts, Chapter 16). Then he had passed through Amphipolis and Apollonia until he came to Thessalonica. There the preaching of Paul and Silas stirred up the Jews who gathered a multitude to attack the Apostles (Acts 17:5). Philippians 4:16 states that the saints in Philippi sent money on more than one occasion to Paul while he was preaching in Thessalonica.

Because of the persecution, the saints in Thessalonica sent Paul and Silas on to Berea (Acts 17:19).

The Jews of Thessalonica followed the apostles to Berea and stirred up the Bereans against them (Acts 17:13). At this point, the Berean saints conducted Paul to the sea and on to Athens. From Athens, Paul went to Corinth (Acts 18:1).

When Paul left Berea he was departing from the region of Macedonia and proceeding toward Achaia, in which the city of Corinth was located. The saints in Philippi were the only believers who continued to support Paul after he left Macedonia.

And when I was present with you [Corinthians], and wanted, I was chargeable to no man: for that which was lacking to me the brothers which came from Macedonia [Philippi of Macedonia] supplied: and in all things I have kept myself from being burdensome unto you, and so will I keep myself. (II Corinthians 11:9)