View source for 18:24 Does this mean that Babylon the city is responsible for the death of every saint and prophet slain on the earth throughout history?

==17:18 What great city is referred to here?== 
The great city referred to here is the literal city of Babylon - seat of the apostate religious system which the woman, Babylon the Great, the mother of harlots, and abominations of the earth symbolizes. 

The woman and Babylon are two facets of the same city and power: They will both make nations drunk with the wine of their fornications, and be responsible for the death of great multitudes of believers during the tribulation ('''cp''' Rev 6:9-11; 7:9-14; 17:1-6 with Re 18:2-3, 7, 9, 24). 

See also comments on Rev 17:1-6 and 18:1-3.

[[Revelation:-]]